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TADs are 3D structural units of higher-order chromosome organization in Drosophila

Deciphering the rules of genome folding in the cell nucleus is essential to understand its functions. Recent chromosome conformation capture (Hi-C) studies have revealed that the genome is partitioned into topologically associating domains (TADs), which demarcate functional epigenetic domains define...

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Detalles Bibliográficos
Autores principales: Szabo, Quentin, Jost, Daniel, Chang, Jia-Ming, Cattoni, Diego I., Papadopoulos, Giorgio L., Bonev, Boyan, Sexton, Tom, Gurgo, Julian, Jacquier, Caroline, Nollmann, Marcelo, Bantignies, Frédéric, Cavalli, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829972/
https://www.ncbi.nlm.nih.gov/pubmed/29503869
http://dx.doi.org/10.1126/sciadv.aar8082