Cargando…
TADs are 3D structural units of higher-order chromosome organization in Drosophila
Deciphering the rules of genome folding in the cell nucleus is essential to understand its functions. Recent chromosome conformation capture (Hi-C) studies have revealed that the genome is partitioned into topologically associating domains (TADs), which demarcate functional epigenetic domains define...
Autores principales: | Szabo, Quentin, Jost, Daniel, Chang, Jia-Ming, Cattoni, Diego I., Papadopoulos, Giorgio L., Bonev, Boyan, Sexton, Tom, Gurgo, Julian, Jacquier, Caroline, Nollmann, Marcelo, Bantignies, Frédéric, Cavalli, Giacomo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829972/ https://www.ncbi.nlm.nih.gov/pubmed/29503869 http://dx.doi.org/10.1126/sciadv.aar8082 |
Ejemplares similares
-
Regulation of single-cell genome organization into TADs and chromatin nanodomains
por: Szabo, Quentin, et al.
Publicado: (2020) -
3D chromatin interactions involving Drosophila insulators are infrequent but preferential and arise before TADs and transcription
por: Messina, Olivier, et al.
Publicado: (2023) -
Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila
por: Ciabrelli, Filippo, et al.
Publicado: (2017) -
Principles of genome folding into topologically associating domains
por: Szabo, Quentin, et al.
Publicado: (2019) -
Single-cell absolute contact probability detection reveals chromosomes are organized by multiple low-frequency yet specific interactions
por: Cattoni, Diego I., et al.
Publicado: (2017)