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Epigenetic Activation of Pro-angiogenic Signaling Pathways in Human Endothelial Progenitors Increases Vasculogenesis

Human endothelial colony-forming cells (ECFCs) represent a promising source of adult stem cells for vascular repair, yet their regenerative capacity is limited. Here, we set out to understand the molecular mechanism restricting the repair function of ECFCs. We found that key pro-angiogenic pathways...

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Detalles Bibliográficos
Autores principales: Fraineau, Sylvain, Palii, Carmen G., McNeill, Brian, Ritso, Morten, Shelley, William C., Prasain, Nutan, Chu, Alphonse, Vion, Elodie, Rieck, Kristy, Nilufar, Sharmin, Perkins, Theodore J., Rudnicki, Michael A., Allan, David S., Yoder, Mervin C., Suuronen, Erik J., Brand, Marjorie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830028/
https://www.ncbi.nlm.nih.gov/pubmed/29033304
http://dx.doi.org/10.1016/j.stemcr.2017.09.009