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Irradiated Human Umbilical Vein Endothelial Cells Undergo Endothelial-Mesenchymal Transition via the Snail/miR-199a-5p Axis to Promote the Differentiation of Fibroblasts into Myofibroblasts

Radiation induced pulmonary fibrosis (RIPF) is one of the major side effects of radiotherapy for lung cancer. Previous studies have shown that endothelial cells and activated myofibroblasts play a key role in RIPF. However, the interaction between irradiated endothelial cells and activation of myofi...

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Detalles Bibliográficos
Autores principales: Yi, Minxiao, Liu, Bo, Tang, Yang, Li, Fang, Qin, Wan, Yuan, Xianglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830288/
https://www.ncbi.nlm.nih.gov/pubmed/29619372
http://dx.doi.org/10.1155/2018/4135806