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Modulation of human airway smooth muscle biology by human adipocytes

BACKGROUND: Asthma and obesity, two growing epidemics worldwide, may share an underlying causal relationship. Airway hyperresponsiveness (AHR), a defining component of asthma, has been documented in both ‘obese’ animal models and non-asthmatic obese individuals. However, there is a paucity of eviden...

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Detalles Bibliográficos
Autores principales: Giesler, Amanda, Mukherjee, Manali, Radford, Katherine, Janssen, Luke, Nair, Parameswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830317/
https://www.ncbi.nlm.nih.gov/pubmed/29486749
http://dx.doi.org/10.1186/s12931-018-0741-z