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Immune checkpoint inhibitor (nivolumab)-associated kidney injury and the importance of recognizing concomitant medications known to cause acute tubulointerstitial nephritis: a case report

BACKGROUND: Acute tubulointerstitial nephritis (ATIN) has been increasingly recognized as an important manifestation of kidney injury associated with the use of immune checkpoint inhibitors (anti-PD-1 and anti-CTLA-4). While the exact pathophysiology remains unknown, corticosteroids are the mainstay...

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Detalles Bibliográficos
Autores principales: Koda, Ryo, Watanabe, Hirofumi, Tsuchida, Masafumi, Iino, Noriaki, Suzuki, Kazuo, Hasegawa, Go, Imai, Naofumi, Narita, Ichiei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830324/
https://www.ncbi.nlm.nih.gov/pubmed/29486725
http://dx.doi.org/10.1186/s12882-018-0848-y