Adaptive designs in clinical trials: why use them, and how to run and report them

Adaptive designs can make clinical trials more flexible by utilising results accumulating in the trial to modify the trial’s course in accordance with pre-specified rules. Trials with an adaptive design are often more efficient, informative and ethical than trials with a traditional fixed design sin...

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Detalles Bibliográficos
Autores principales: Pallmann, Philip, Bedding, Alun W., Choodari-Oskooei, Babak, Dimairo, Munyaradzi, Flight, Laura, Hampson, Lisa V., Holmes, Jane, Mander, Adrian P., Odondi, Lang’o, Sydes, Matthew R., Villar, Sofía S., Wason, James M. S., Weir, Christopher J., Wheeler, Graham M., Yap, Christina, Jaki, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830330/
https://www.ncbi.nlm.nih.gov/pubmed/29490655
http://dx.doi.org/10.1186/s12916-018-1017-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830330/
https://www.ncbi.nlm.nih.gov/pubmed/29490655
http://dx.doi.org/10.1186/s12916-018-1017-7

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