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Ubiquitin-proteasome system modulates zygotic genome activation in early mouse embryos and influences full-term development

Maternal RNA/protein degradation and zygotic genome activation (ZGA), occurring during maternal-to-zygotic transition (MZT), are the first essential events for the development of pre-implantation embryos. Previously, we have shown the importance of the ubiquitin-proteasome system (UPS) for initiatio...

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Detalles Bibliográficos
Autores principales: HIGUCHI, Chika, SHIMIZU, Natsumi, SHIN, Seung-Wook, MORITA, Kohtaro, NAGAI, Kouhei, ANZAI, Masayuki, KATO, Hiromi, MITANI, Tasuku, YAMAGATA, Kazuo, HOSOI, Yoshihiko, MIYAMOTO, Kei, MATSUMOTO, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830360/
https://www.ncbi.nlm.nih.gov/pubmed/29212961
http://dx.doi.org/10.1262/jrd.2017-127