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Mancozeb impairs the ultrastructure of mouse granulosa cells in a dose-dependent manner

Mancozeb, an ethylene bis-dithiocarbamate, is widely used as a fungicide and exerts reproductive toxicity in vivo and in vitro in mouse oocytes by altering spindle morphology and impairing the ability to fertilize. Mancozeb also induces a premalignant status in mouse granulosa cells (GCs) cultured i...

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Detalles Bibliográficos
Autores principales: PALMERINI, Maria Grazia, BELLI, Manuel, NOTTOLA, Stefania Annarita, MIGLIETTA, Selenia, BIANCHI, Serena, BERNARDI, Sara, ANTONOULI, Sevastiani, CECCONI, Sandra, FAMILIARI, Giuseppe, MACCHIARELLI, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830361/
https://www.ncbi.nlm.nih.gov/pubmed/29225323
http://dx.doi.org/10.1262/jrd.2017-143