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Chemotherapy-induced differential cell cycle arrest in B-cell lymphomas affects their sensitivity to Wee1 inhibition

Chemotherapeutic agents, e.g., cytarabine and doxorubicin, cause DNA damage. However, it remains unknown whether such agents differentially regulate cell cycle arrest in distinct types of B-cell lymphomas, and whether this phenotype can be exploited for developing new therapies. We treated various t...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoguang, Chen, Zhangguo, Mishra, Ameet K., Silva, Alexa, Ren, Wenhua, Pan, Zenggang, Wang, Jing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830367/
https://www.ncbi.nlm.nih.gov/pubmed/29217775
http://dx.doi.org/10.3324/haematol.2017.175992