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Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies

In patients with dysfunctions of the Ca(2+) channel ORAI1, stromal interaction molecule 1 (STIM1) or integrin-regulating kindlin-3 (FERMT3), severe immunodeficiency is frequently linked to abnormal platelet activity. In this paper, we studied platelet responsiveness by multiparameter assessment of w...

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Detalles Bibliográficos
Autores principales: Nagy, Magdolna, Mastenbroek, Tom G., Mattheij, Nadine J.A., de Witt, Susanne, Clemetson, Kenneth J., Kirschner, Janbernd, Schulz, Ansgar S., Vraetz, Thomas, Speckmann, Carsten, Braun, Attila, Cosemans, Judith M.E.M., Zieger, Barbara, Heemskerk, Johan W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830379/
https://www.ncbi.nlm.nih.gov/pubmed/29242293
http://dx.doi.org/10.3324/haematol.2017.176974