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Variable impairment of platelet functions in patients with severe, genetically linked immune deficiencies
In patients with dysfunctions of the Ca(2+) channel ORAI1, stromal interaction molecule 1 (STIM1) or integrin-regulating kindlin-3 (FERMT3), severe immunodeficiency is frequently linked to abnormal platelet activity. In this paper, we studied platelet responsiveness by multiparameter assessment of w...
Autores principales: | Nagy, Magdolna, Mastenbroek, Tom G., Mattheij, Nadine J.A., de Witt, Susanne, Clemetson, Kenneth J., Kirschner, Janbernd, Schulz, Ansgar S., Vraetz, Thomas, Speckmann, Carsten, Braun, Attila, Cosemans, Judith M.E.M., Zieger, Barbara, Heemskerk, Johan W.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830379/ https://www.ncbi.nlm.nih.gov/pubmed/29242293 http://dx.doi.org/10.3324/haematol.2017.176974 |
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