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Unattached kinetochores drive their own capturing by sequestering a CLASP

Kinetochores that are not attached to microtubules prevent chromosome missegregation via the spindle assembly checkpoint. We show that they also promote their own capturing. Similar to what governs the localization of spindle assembly checkpoint proteins, the phosphorylation of Spc105 by Mps1 allows...

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Detalles Bibliográficos
Autores principales: Kolenda, Caroline, Ortiz, Jennifer, Pelzl, Marina, Norell, Sarina, Schmeiser, Verena, Lechner, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830412/
https://www.ncbi.nlm.nih.gov/pubmed/29491436
http://dx.doi.org/10.1038/s41467-018-03108-z