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Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor

Single-cell RNA-sequencing (scRNA-seq) technology provides a new avenue to discover and characterize cell types; however, the experiment-specific technical biases and analytic variability inherent to current pipelines may undermine its replicability. Meta-analysis is further hampered by the use of a...

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Detalles Bibliográficos
Autores principales: Crow, Megan, Paul, Anirban, Ballouz, Sara, Huang, Z. Josh, Gillis, Jesse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830442/
https://www.ncbi.nlm.nih.gov/pubmed/29491377
http://dx.doi.org/10.1038/s41467-018-03282-0