Nox4 is a Target for Tuberin Deficiency Syndrome

The mechanism by which TSC2 inactivation or deficiency contributes to the pathology of tuberous sclerosis complex (TSC) is not fully clear. We show that renal angiomyolipomas from TSC patients and kidney cortex from Tsc2+/− mice exhibit elevated levels of reactive oxygen species (ROS). Downregulatio...

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Detalles Bibliográficos
Autores principales: Shi, Qian, Viswanadhapalli, Suryavathi, Friedrichs, William E., Velagapudi, Chakradhar, Szyndralewiez, Cédric, Bansal, Shweta, Bhat, Manzoor A., Choudhury, Goutam Ghosh, Abboud, Hanna E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830489/
https://www.ncbi.nlm.nih.gov/pubmed/29491408
http://dx.doi.org/10.1038/s41598-018-21838-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830489/
https://www.ncbi.nlm.nih.gov/pubmed/29491408
http://dx.doi.org/10.1038/s41598-018-21838-4

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