The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock

Resistance to the intestinal parasitic helminth Trichuris muris requires T-helper 2 (T(H)2) cellular and associated IgG1 responses, with expulsion typically taking up to 4 weeks in mice. Here, we show that the time-of-day of the initial infection affects efficiency of worm expulsion, with strong T(H...

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Detalles Bibliográficos
Autores principales: Hopwood, Thomas W., Hall, Sarah, Begley, Nicola, Forman, Ruth, Brown, Sheila, Vonslow, Ryan, Saer, Ben, Little, Matthew C., Murphy, Emma A., Hurst, Rebecca J., Ray, David W., MacDonald, Andrew S., Brass, Andy, Bechtold, David A., Gibbs, Julie E., Loudon, Andrew S., Else, Kathryn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830501/
https://www.ncbi.nlm.nih.gov/pubmed/29491349
http://dx.doi.org/10.1038/s41598-018-22021-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830501/
https://www.ncbi.nlm.nih.gov/pubmed/29491349
http://dx.doi.org/10.1038/s41598-018-22021-5

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