Disruption of the open conductance in the β-tongue mutants of Cytolysin A

Cytolysin A (ClyA) is a water-soluble alpha pore-forming toxin that assembles to form an oligomeric pore on host cell membranes. The ClyA monomer possesses an α-helical bundle with a β-sheet subdomain (the β-tongue) previously believed to be critical for pore assembly and/or insertion. Oligomerizati...

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Detalles Bibliográficos
Autores principales: Fahie, Monifa A., Liang, Lucas, Avelino, Alzira R., Pham, Bach, Limpikirati, Patanachai, Vachet, Richard W., Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830503/
https://www.ncbi.nlm.nih.gov/pubmed/29491391
http://dx.doi.org/10.1038/s41598-018-22009-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830503/
https://www.ncbi.nlm.nih.gov/pubmed/29491391
http://dx.doi.org/10.1038/s41598-018-22009-1

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