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Role of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury

Intestinal ischemia-reperfusion (I/R) may cause acute systemic and lung inflammation. However, the detailed mechanism of this inflammatory cascade has not been fully elucidated. Inactive rhomboid protein 2 (iRhom2) is essential for the maturation of TNF-α converting enzyme (TACE), which is required...

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Detalles Bibliográficos
Autores principales: Kim, Jee Hyun, Kim, Jihye, Chun, Jaeyoung, Lee, Changhyun, Im, Jong Pil, Kim, Joo Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830505/
https://www.ncbi.nlm.nih.gov/pubmed/29491382
http://dx.doi.org/10.1038/s41598-018-22218-8