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JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress
Post-translational modifications of histones, constitutive components of chromatin, regulate chromatin compaction and control all DNA-based cellular processes. C. elegans JMJD-1.2, a member of the KDM7 family, is a demethylase active towards several lysine residues on Histone 3 (H3), but its contrib...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830613/ https://www.ncbi.nlm.nih.gov/pubmed/29491442 http://dx.doi.org/10.1038/s41598-018-21914-9 |