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JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress

Post-translational modifications of histones, constitutive components of chromatin, regulate chromatin compaction and control all DNA-based cellular processes. C. elegans JMJD-1.2, a member of the KDM7 family, is a demethylase active towards several lysine residues on Histone 3 (H3), but its contrib...

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Detalles Bibliográficos
Autores principales: Myers, Toshia R., Amendola, Pier Giorgio, Lussi, Yvonne C., Salcini, Anna Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830613/
https://www.ncbi.nlm.nih.gov/pubmed/29491442
http://dx.doi.org/10.1038/s41598-018-21914-9

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