Inhibition of IL‐6‐JAK/Stat3 signaling in castration‐resistant prostate cancer cells enhances the NK cell‐mediated cytotoxicity via alteration of PD‐L1/NKG2D ligand levels

To investigate whether IL‐6 signaling affects the susceptibility of castration‐resistant prostate cancer (CRPC) cells to cytotoxic action of natural killer (NK) cells, CRPC cell lines (having different IL‐6 levels) were developed by lentiviral transduction. While observing no secreted IL‐6 level in...

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Detalles Bibliográficos
Autores principales: Xu, LiJun, Chen, XiaoDong, Shen, MingJing, Yang, Dong‐Rong, Fang, Laifu, Weng, Guobin, Tsai, Ying, Keng, Peter C., Chen, Yuhchyau, Lee, Soo Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830627/
https://www.ncbi.nlm.nih.gov/pubmed/28865178
http://dx.doi.org/10.1002/1878-0261.12135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830627/
https://www.ncbi.nlm.nih.gov/pubmed/28865178
http://dx.doi.org/10.1002/1878-0261.12135

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