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MAD2L2 inhibits colorectal cancer growth by promoting NCOA3 ubiquitination and degradation

Nuclear receptor coactivator 3 (NCOA3) is a transcriptional coactivator that has elevated expression in multiple tumor types, including colorectal cancer (CRC). However, the molecular mechanisms that regulate the tumorigenic functions of NCOA3 in CRC remain largely unknown. In this study, we aimed t...

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Detalles Bibliográficos
Autores principales: Li, Yixin, Li, Liren, Chen, Miao, Yu, Xinfa, Gu, Zhuoyu, Qiu, Huijuan, Qin, Ge, Long, Qian, Fu, Xiaoyan, Liu, Tianze, Li, Wenbin, Huang, Wenlin, Shi, Dingbo, Kang, Tiebang, Luo, Meihua, Wu, Xiaojun, Deng, Wuguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830628/
https://www.ncbi.nlm.nih.gov/pubmed/29360267
http://dx.doi.org/10.1002/1878-0261.12173