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Inhibition of VEGF‐dependent angiogenesis and tumor angiogenesis by an optimized antibody targeting CLEC14a

The C‐type lectin‐like domain of CLEC14a (CLEC14a‐C‐type lectin‐like domain [CTLD]) is a key domain that mediates endothelial cell–cell contacts in angiogenesis. However, the role of CLEC14a‐CTLD in pathological angiogenesis has not yet been clearly elucidated. In this study, through complementarity...

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Detalles Bibliográficos
Autores principales: Kim, Taek‐Keun, Park, Chang Sik, Jang, Jihye, Kim, Mi Ra, Na, Hee‐Jun, Lee, Kangseung, Kim, Hyun Jung, Heo, Kyun, Yoo, Byong Chul, Kim, Young‐Myeong, Lee, Je‐Wook, Kim, Su Jin, Kim, Eun Sung, Kim, Dae Young, Cha, Kiweon, Lee, Tae Gyu, Lee, Sukmook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830631/
https://www.ncbi.nlm.nih.gov/pubmed/29316206
http://dx.doi.org/10.1002/1878-0261.12169