Novel FR-900493 Analogues That Inhibit the Outgrowth of Clostridium difficile Spores

[Image: see text] The spectrum of antibacterial activity for the nucleoside antibiotic FR-900493 (1) can be extended by chemical modifications. We have generated a small focused library based on the structure of 1 and identified UT-17415 (9), UT-17455 (10), UT-17460 (11), and UT-17465 (12), which ex...

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Detalles Bibliográficos
Autores principales: Mitachi, Katsuhiko, Yun, Hyun Gi, Kurosu, Sara M., Eslamimehr, Shakiba, Lemieux, Maddie R., Klaić, Lada, Clemons, William M., Kurosu, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830699/
https://www.ncbi.nlm.nih.gov/pubmed/29503973
http://dx.doi.org/10.1021/acsomega.7b01740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830699/
https://www.ncbi.nlm.nih.gov/pubmed/29503973
http://dx.doi.org/10.1021/acsomega.7b01740

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