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A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative

A facile synthetic method was developed for a novel acid-sensitive camptothecin norcantharidin acid ester derivative I. The total yield can reach 71%. This method provides several advantages, including high yield and simple working procedure for the synthesis of analogues. The new synthetic compound...

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Detalles Bibliográficos
Autores principales: Zhao, Changkuo, Wang, Xianheng, Yang, Fuhong, Gao, Lei, Wang, Yuhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830714/
https://www.ncbi.nlm.nih.gov/pubmed/29515825
http://dx.doi.org/10.1098/rsos.170842