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A simple route to a novel acid-sensitive 20(S)-O-linked camptothecin norcantharidin acid ester derivative
A facile synthetic method was developed for a novel acid-sensitive camptothecin norcantharidin acid ester derivative I. The total yield can reach 71%. This method provides several advantages, including high yield and simple working procedure for the synthesis of analogues. The new synthetic compound...
Autores principales: | Zhao, Changkuo, Wang, Xianheng, Yang, Fuhong, Gao, Lei, Wang, Yuhe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830714/ https://www.ncbi.nlm.nih.gov/pubmed/29515825 http://dx.doi.org/10.1098/rsos.170842 |
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