Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species

Protein aggregation into amyloid deposits and oxidative stress are key features of many neurodegenerative disorders including Parkinson's and Alzheimer's disease. We report here the creation of four highly sensitive bifunctional fluorescent probes, capable of H(2)O(2) and/or amyloid aggreg...

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Detalles Bibliográficos
Autores principales: Needham, Lisa-Maria, Weber, Judith, Fyfe, James W. B., Kabia, Omaru M., Do, Dung T., Klimont, Ewa, Zhang, Yu, Rodrigues, Margarida, Dobson, Christopher M., Ghandi, Sonia, Bohndiek, Sarah E., Snaddon, Thomas N., Lee, Steven F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830749/
https://www.ncbi.nlm.nih.gov/pubmed/29515860
http://dx.doi.org/10.1098/rsos.171399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830749/
https://www.ncbi.nlm.nih.gov/pubmed/29515860
http://dx.doi.org/10.1098/rsos.171399

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