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Synthesis of adenosine analogues with indole moiety as human adenosine A(3) receptor ligands

Adenosine is an endogenous modulator exerting its functions through the activation of four adenosine receptor (AR) subtypes, termed A(1), A(2A), A(2B) and A(3), which belong to the G-protein-coupled receptor superfamily. The human A(3)AR (hA(3)AR) subtype is implicated in several cytoprotective func...

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Detalles Bibliográficos
Autores principales: Xia, Yan, Zheng, Xiliang, Wang, Erkang, Li, Dongfeng, Hou, Ruibin, Wang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830761/
https://www.ncbi.nlm.nih.gov/pubmed/29515872
http://dx.doi.org/10.1098/rsos.171596