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Telmisartan and esculetin combination ameliorates type 2 diabetic cardiomyopathy by reversal of H3, H2A, and H2B histone modifications

OBJECTIVES: Although cardioprotective effects of telmisartan are well explored, its effects on epigenetic alterations associated with type 2 diabetic (T2D) cardiomyopathy remain unmapped. Thus, the present study was designed to evaluate the potential of esculetin and telmisartan combination to rever...

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Detalles Bibliográficos
Autores principales: Kadakol, Almesh, Malek, Vajir, Goru, Santosh Kumar, Pandey, Anuradha, Gaikwad, Anil Bhanudas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830845/
https://www.ncbi.nlm.nih.gov/pubmed/29515275
http://dx.doi.org/10.4103/ijp.IJP_710_16