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Transplanted Donor- or Stem Cell-Derived Cone Photoreceptors Can Both Integrate and Undergo Material Transfer in an Environment-Dependent Manner

Human vision relies heavily upon cone photoreceptors, and their loss results in permanent visual impairment. Transplantation of healthy photoreceptors can restore visual function in models of inherited blindness, a process previously understood to arise by donor cell integration within the host reti...

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Detalles Bibliográficos
Autores principales: Waldron, Paul V., Di Marco, Fabiana, Kruczek, Kamil, Ribeiro, Joana, Graca, Anna B., Hippert, Claire, Aghaizu, Nozie D., Kalargyrou, Aikaterini A., Barber, Amanda C., Grimaldi, Giulia, Duran, Yanai, Blackford, Samuel J.I., Kloc, Magdalena, Goh, Debbie, Zabala Aldunate, Eduardo, Sampson, Robert D., Bainbridge, James W.B., Smith, Alexander J., Gonzalez-Cordero, Anai, Sowden, Jane C., Ali, Robin R., Pearson, Rachael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830910/
https://www.ncbi.nlm.nih.gov/pubmed/29307580
http://dx.doi.org/10.1016/j.stemcr.2017.12.008