p62 filaments capture and present ubiquitinated cargos for autophagy

The removal of misfolded, ubiquitinated proteins is an essential part of the protein quality control. The ubiquitin‐proteasome system (UPS) and autophagy are two interconnected pathways that mediate the degradation of such proteins. During autophagy, ubiquitinated proteins are clustered in a p62‐dep...

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Detalles Bibliográficos
Autores principales: Zaffagnini, Gabriele, Savova, Adriana, Danieli, Alberto, Romanov, Julia, Tremel, Shirley, Ebner, Michael, Peterbauer, Thomas, Sztacho, Martin, Trapannone, Riccardo, Tarafder, Abul K, Sachse, Carsten, Martens, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830917/
https://www.ncbi.nlm.nih.gov/pubmed/29343546
http://dx.doi.org/10.15252/embj.201798308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830917/
https://www.ncbi.nlm.nih.gov/pubmed/29343546
http://dx.doi.org/10.15252/embj.201798308

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