KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis

Epithelial tissues rely on a highly coordinated balance between self-renewal, proliferation, and differentiation, disruption of which may drive carcinogenesis. The epigenetic regulator KMT2D (MLL4) is one of the most frequently mutated genes in all cancers, particularly epithelial cancers, yet its n...

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Detalles Bibliográficos
Autores principales: Lin-Shiao, Enrique, Lan, Yemin, Coradin, Mariel, Anderson, Amy, Donahue, Greg, Simpson, Cory L., Sen, Payel, Saffie, Rizwan, Busino, Luca, Garcia, Benjamin A., Berger, Shelley L., Capell, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830930/
https://www.ncbi.nlm.nih.gov/pubmed/29440247
http://dx.doi.org/10.1101/gad.306241.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830930/
https://www.ncbi.nlm.nih.gov/pubmed/29440247
http://dx.doi.org/10.1101/gad.306241.117

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