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Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming

B-cell fate determination requires the action of transcription factors that operate in a regulatory network to activate B-lineage genes and repress lineage-inappropriate genes. However, the dynamics and hierarchy of events in B-cell programming remain obscure. To uncouple the dynamics of transcripti...

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Detalles Bibliográficos
Autores principales: Li, Rui, Cauchy, Pierre, Ramamoorthy, Senthilkumar, Boller, Sören, Chavez, Lukas, Grosschedl, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830932/
https://www.ncbi.nlm.nih.gov/pubmed/29440261
http://dx.doi.org/10.1101/gad.309583.117