Cargando…
Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming
B-cell fate determination requires the action of transcription factors that operate in a regulatory network to activate B-lineage genes and repress lineage-inappropriate genes. However, the dynamics and hierarchy of events in B-cell programming remain obscure. To uncouple the dynamics of transcripti...
Autores principales: | Li, Rui, Cauchy, Pierre, Ramamoorthy, Senthilkumar, Boller, Sören, Chavez, Lukas, Grosschedl, Rudolf |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830932/ https://www.ncbi.nlm.nih.gov/pubmed/29440261 http://dx.doi.org/10.1101/gad.309583.117 |
Ejemplares similares
-
Tnpo3 enables EBF1 function in conditions of antagonistic Notch signaling
por: Bayer, Marc, et al.
Publicado: (2022) -
Interaction of CCR4–NOT with EBF1 regulates gene-specific transcription and mRNA stability in B lymphopoiesis
por: Yang, Cheng-Yuan, et al.
Publicado: (2016) -
EBF1 and Pax5 safeguard leukemic transformation by limiting IL-7 signaling, Myc expression, and folate metabolism
por: Ramamoorthy, Senthilkumar, et al.
Publicado: (2020) -
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors
por: Lenaerts, Aurelie, et al.
Publicado: (2022) -
Regulation of proliferation and survival of B-lymphocytes by Ebf1 - implications in leukaemia
por: Győry, Ildikó, et al.
Publicado: (2013)