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SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells

Scarce access to primary samples and lack of efficient protocols to generate oligodendrocytes (OLs) from human pluripotent stem cells (hPSCs) are hampering our understanding of OL biology and the development of novel therapies. Here, we demonstrate that overexpression of the transcription factor SOX...

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Detalles Bibliográficos
Autores principales: García-León, Juan Antonio, Kumar, Manoj, Boon, Ruben, Chau, David, One, Jennifer, Wolfs, Esther, Eggermont, Kristel, Berckmans, Pieter, Gunhanlar, Nilhan, de Vrij, Femke, Lendemeijer, Bas, Pavie, Benjamin, Corthout, Nikky, Kushner, Steven A., Dávila, José Carlos, Lambrichts, Ivo, Hu, Wei-Shou, Verfaillie, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830935/
https://www.ncbi.nlm.nih.gov/pubmed/29337119
http://dx.doi.org/10.1016/j.stemcr.2017.12.014