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XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer
Pig cloning by somatic cell nuclear transfer (SCNT) remains extremely inefficient, and many cloned embryos undergo abnormal development. Here, by profiling transcriptome expression, we observed dysregulated chromosome-wide gene expression in every chromosome and identified a considerable number of g...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830944/ https://www.ncbi.nlm.nih.gov/pubmed/29337117 http://dx.doi.org/10.1016/j.stemcr.2017.12.015 |