XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer

Pig cloning by somatic cell nuclear transfer (SCNT) remains extremely inefficient, and many cloned embryos undergo abnormal development. Here, by profiling transcriptome expression, we observed dysregulated chromosome-wide gene expression in every chromosome and identified a considerable number of g...

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Detalles Bibliográficos
Autores principales: Ruan, Degong, Peng, Jiangyun, Wang, Xiaoshan, Ouyang, Zhen, Zou, Qingjian, Yang, Yi, Chen, Fangbing, Ge, Weikai, Wu, Han, Liu, Zhaoming, Zhao, Yu, Zhao, Bentian, Zhang, Quanjun, Lai, Chengdan, Fan, Nana, Zhou, Zhiwei, Liu, Qishuai, Li, Nan, Jin, Qin, Shi, Hui, Xie, Jingke, Song, Hong, Yang, Xiaoyu, Chen, Jiekai, Wang, Kepin, Li, Xiaoping, Lai, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830944/
https://www.ncbi.nlm.nih.gov/pubmed/29337117
http://dx.doi.org/10.1016/j.stemcr.2017.12.015

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