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Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance

The heterochromatin protein 1 (HP1) family is involved in various functions with maintenance of chromatin structure. During murine somatic cell reprogramming, we find that early depletion of HP1γ reduces the generation of induced pluripotent stem cells, while late depletion enhances the process, wit...

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Detalles Bibliográficos
Autores principales: Zaidan, Nur Zafirah, Walker, Kolin J., Brown, Jaime E., Schaffer, Leah V., Scalf, Mark, Shortreed, Michael R., Iyer, Gopal, Smith, Lloyd M., Sridharan, Rupa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830946/
https://www.ncbi.nlm.nih.gov/pubmed/29358085
http://dx.doi.org/10.1016/j.stemcr.2017.12.016