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Compartmentalization of HP1 Proteins in Pluripotency Acquisition and Maintenance
The heterochromatin protein 1 (HP1) family is involved in various functions with maintenance of chromatin structure. During murine somatic cell reprogramming, we find that early depletion of HP1γ reduces the generation of induced pluripotent stem cells, while late depletion enhances the process, wit...
Autores principales: | Zaidan, Nur Zafirah, Walker, Kolin J., Brown, Jaime E., Schaffer, Leah V., Scalf, Mark, Shortreed, Michael R., Iyer, Gopal, Smith, Lloyd M., Sridharan, Rupa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830946/ https://www.ncbi.nlm.nih.gov/pubmed/29358085 http://dx.doi.org/10.1016/j.stemcr.2017.12.016 |
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