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MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1

Human pluripotent stem cells (hPSCs) provide an unlimited source for generating various kinds of functional blood cells. However, efficient strategies for generating large-scale functional blood cells from hPSCs are still lacking, and the mechanism underlying human hematopoiesis remains largely unkn...

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Detalles Bibliográficos
Autores principales: Wang, Hongtao, Liu, Cuicui, Liu, Xin, Wang, Mengge, Wu, Dan, Gao, Jie, Su, Pei, Nakahata, Tatsutoshi, Zhou, Wen, Xu, Yuanfu, Shi, Lihong, Ma, Feng, Zhou, Jiaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830947/
https://www.ncbi.nlm.nih.gov/pubmed/29358086
http://dx.doi.org/10.1016/j.stemcr.2017.12.017