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In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

Due to differences across species, the mechanisms of cell fate decisions determined in mice cannot be readily extrapolated to humans. In this study, we developed a feeder- and xeno-free culture protocol that efficiently induced human pluripotent stem cells (iPSCs) into PLZF+/GPR125+/CD90+ spermatogo...

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Detalles Bibliográficos
Autores principales: Zhao, Yuncheng, Ye, Shicheng, Liang, Dongli, Wang, Pengxiang, Fu, Jing, Ma, Qing, Kong, Ruijiao, Shi, Linghong, Gong, Xueping, Chen, Wei, Ding, Wubin, Yang, Wenjing, Zhu, Zijue, Chen, Huixing, Sun, Xiaoxi, Zhu, Jun, Li, Zheng, Wang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830957/
https://www.ncbi.nlm.nih.gov/pubmed/29398481
http://dx.doi.org/10.1016/j.stemcr.2018.01.001