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Testicular Architecture Is Critical for Mediation of Retinoic Acid Responsiveness by Undifferentiated Spermatogonial Subtypes in the Mouse

Spermatogenesis requires retinoic acid (RA) induction of the undifferentiated to differentiating transition in transit amplifying (TA) progenitor spermatogonia, whereas continuity of the spermatogenic lineage relies on the RA response being suppressed in spermatogonial stem cells (SSCs). Here, we di...

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Detalles Bibliográficos
Autores principales: Lord, Tessa, Oatley, Melissa J., Oatley, Jon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830974/
https://www.ncbi.nlm.nih.gov/pubmed/29398482
http://dx.doi.org/10.1016/j.stemcr.2018.01.003