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Insulin signaling as a potential natural killer cell checkpoint in fatty liver disease

Insulin resistance is a key risk factor in the progression of nonalcoholic fatty liver disease (NAFLD) and may lead to liver fibrosis. Natural killer (NK) cells are thought to exert an antifibrotic effect through their killing of activated hepatic stellate cells (HSCs). Here, we investigated how the...

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Detalles Bibliográficos
Autores principales: Amer, Johnny, Salhab, Ahmad, Noureddin, Mazen, Doron, Sarit, Abu‐Tair, Lina, Ghantous, Rami, Mahamid, Mahmud, Safadi, Rifaat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831020/
https://www.ncbi.nlm.nih.gov/pubmed/29507903
http://dx.doi.org/10.1002/hep4.1146