Improved oxygenation dramatically alters metabolism and gene expression in cultured primary mouse hepatocytes

Primary hepatocyte culture is an important in vitro system for the study of liver functions. In vivo, hepatocytes have high oxidative metabolism. However, oxygen supply by means of diffusion in in vitro static cultures is much less than that by blood circulation in vivo. Therefore, we investigated w...

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Detalles Bibliográficos
Autores principales: Gilglioni, Eduardo H., Chang, Jung‐Chin, Duijst, Suzanne, Go, Simei, Adam, Aziza A. A., Hoekstra, Ruurdtje, Verhoeven, Arthur J., Ishii‐Iwamoto, Emy L., Oude Elferink, Ronald P.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831026/
https://www.ncbi.nlm.nih.gov/pubmed/29507904
http://dx.doi.org/10.1002/hep4.1140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831026/
https://www.ncbi.nlm.nih.gov/pubmed/29507904
http://dx.doi.org/10.1002/hep4.1140

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