Cargando…
Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells
Activation of ERK1/2 implies the phosphorylation of tyrosine (pTyr) and threonine (pThr) by MEK1/2; both reactions were thought to be cytoplasmic, promoting ERK to reach the nucleus where it activates several transcription factors. In addition, H(2)O(2) concentrations are known to modulate ERK intra...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831038/ https://www.ncbi.nlm.nih.gov/pubmed/29489891 http://dx.doi.org/10.1371/journal.pone.0193022 |