Does the rising placebo response impact antihypertensive clinical trial outcomes? An analysis of data from the Food and Drug Administration 1990-2016

BACKGROUND: Recent studies show that placebo response has grown significantly over time in clinical trials for antidepressants, ADHD medications, antiepileptics, and antidiabetics. Contrary to expectations, trial outcome measures and success rates have not been impacted. This study aimed to see if t...

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Detalles Bibliográficos
Autores principales: Khan, Arif, Fahl Mar, Kaysee, Schilling, Joshua, Brown, Walter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831097/
https://www.ncbi.nlm.nih.gov/pubmed/29489874
http://dx.doi.org/10.1371/journal.pone.0193043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831097/
https://www.ncbi.nlm.nih.gov/pubmed/29489874
http://dx.doi.org/10.1371/journal.pone.0193043

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