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Transitional basal cells at the squamous-columnar junction generate Barrett’s oesophagus
In several organ systems the transitional zone between different types of epithelia is a hotspot for pre-neoplastic metaplasia and malignancy(1–3). However, the cell-of-origin for the metaplastic epithelium and subsequent malignancy, remains obscure(1–3). In the case of Barrett’s oesophagus (BE), in...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831195/ https://www.ncbi.nlm.nih.gov/pubmed/29019984 http://dx.doi.org/10.1038/nature24269 |