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The effects of trastuzumab on HER2-mediated cell signaling in CHO cells expressing human HER2
BACKGROUND: Targeted therapy with trastuzumab has become a mainstay for HER2-positive breast cancer without a clear understanding of the mechanism of its action. While many mechanisms have been suggested for the action of trastuzumab, most of them are not substantiated by experimental data. It has b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831215/ https://www.ncbi.nlm.nih.gov/pubmed/29490608 http://dx.doi.org/10.1186/s12885-018-4143-x |