Oncogenic BRAF mutations and p16 expression in melanocytic nevi and melanoma in the Polish population

INTRODUCTION: Twenty-five – fifty percent of skin melanomas arise from nevi. Melanocyte proliferation is activated by BRAF (V600E), then is arrested, but single nevi transform to melanomas. p16 controls arrest, and p16 loss may promote transformation. AIM: To analyze BRAF (V600E), p16 expression and...

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Detalles Bibliográficos
Autores principales: Mackiewicz-Wysocka, Małgorzata, Czerwińska, Patrycja, Filas, Violetta, Bogajewska, Elżbieta, Kubicka, Agata, Przybyła, Anna, Dondajewska, Ewelina, Kolenda, Tomasz, Marszałek, Andrzej, Mackiewicz, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831287/
https://www.ncbi.nlm.nih.gov/pubmed/29507566
http://dx.doi.org/10.5114/ada.2017.71119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831287/
https://www.ncbi.nlm.nih.gov/pubmed/29507566
http://dx.doi.org/10.5114/ada.2017.71119

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