Melatonin-Induced Protective Effects on Cardiomyocytes Against Reperfusion Injury Partly Through Modulation of IP3R and SERCA2a Via Activation of ERK1

BACKGROUND: Melatonin is a neuroendocrine hormone synthesized primarily by the pineal gland that is indicated to effectively prevent myocardial reperfusion injury. It is unclear whether melatonin protects cardiac function from reperfusion injury by modulating intracellular calcium homeostasis. OBJEC...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Shunying, Zhu, Pingjun, Zhou, Hao, Zhang, Ying, Chen, Yundai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831301/
https://www.ncbi.nlm.nih.gov/pubmed/29538523
http://dx.doi.org/10.5935/abc.20180008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831301/
https://www.ncbi.nlm.nih.gov/pubmed/29538523
http://dx.doi.org/10.5935/abc.20180008

Ejemplares similares